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Mutations in PKA catalytic subunit associated with Cushing’s syndrome
1. Somatic mutations resulting in constitutive activation of PRKACA, which encodes the catalytic subunit of protein kinase A, were found in 37% of patients with Cushing’s syndrome due to an adrenal...
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Cushing’s Syndrome – Epidemiology Forecast to 2023
It’s NOT as rare as they thought… Epidemiologists forecast an increase in the diagnosed prevalent cases of CS in the 6MM, from 32,634 diagnosed prevalent cases in 2013 to 34,573 diagnosed prevalent...
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Exophthalmos and Cushing’s Syndrome
A woman experienced red, irritated and bulging eyes. She saw an ophthalmologist who strongly suspected Graves’ ophthalmopathy. However, the patient did not have and never had hyperthyroidism. Indeed,...
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Screening for Cushing’s syndrome: Is it worthwhile?
The data suggests that Cushing is not frequent enough to support the use of routine screening in patients with morbid obesity and type 2 DM. Also only 1 % of hypertensive patients have secondary...
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OR17-Novel Aspects of Adrenal Tumors and the HPA Axis
March 06, 2015 OR17-Novel Aspects of Adrenal Tumors and the HPA Axis Epigenetic modulation of DNA Is associated with fatigue, depression and anxiety in patients with Cushing’s syndrome in remission:...
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Moderately impaired renal function increases morning cortisol and cortisol...
Clin Endocrinol (Oxf). 2015 May 23. doi: 10.1111/cen.12823. [Epub ahead of print] Olsen H1, Mjöman M2. Author information Abstract OBJECTIVE: Patients with incidentally detected adrenal adenomas may...
View ArticleStudy Examines Therapy Options for Post-adrenalectomy Low Glucocorticoid Levels
Hydrocortisone and prednisone have comparable safety and effectiveness when used as glucocorticoid replacement therapy in patients with adrenal adenoma or Cushing’s disease who underwent adrenalectomy,...
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